|
KMID : 1134819980270030508
|
|
Journal of the Korean Society of Food Science and Nutrition
1998 Volume.27 No. 3 p.508 ~ p.517
|
|
|
Effects of Godulbaegi Extracts on the Stability and Fluidity of Phospholipid Liposomal Membranes
|
|
Bae Song-Ja
Rho Sung-Bae
Jung Bok-Mi
|
|
|
Abstract
|
|
|
|
We investigated the effects of godulbaegi extracts on the physiochemical properties of biological membranes such as membrane stability and fluidity employing the phospholipid liposomal membranes as a biomembrane-mimetic system. The addition of the godulbaegi extracts to the phospholipid exerted great effects stabilized the barrier function of the liposomal membranes in proportion to the concentration of the additive and significantly increased the membranes fluidity. The values of the fluorescence polarization of 1,6-diphenyl 1,3.5-hexatriene (DPH) decreased gradually as the temperature increased, and decreased abruptly near the phase transition temperature(T_m) of the liposome from gel to liquid crystalline state as usual. These results suggest that the activities of the godulbaegi extracts to enhance the stability and fluidity of the liposomal membranes have implication in their biological activities.
|
|
|
KEYWORD
|
|
|
Ixeris sonchifolia extracts, liposome, stability, calcein, DPPC
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|